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Browsing College of Sciences and Mathematics by Subject "FLT3 LIGAND"

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Analysis of the developmental stages, kinetics, and phenotypes exhibited by myeloid cells driven by GM-CSF in vitro 

Rogers, Peter B.; Driessnack, Michelle G.; Schwartz, Elizabeth Hiltbold (2025-08-01)
The developmental progression of conventional DC has been quite well defined, yet the developmental pathway of monocyte-derived, GM-CSF-driven DC is less well understood. We addressed this issue by establishing an isolation ...

Development of endocytosis, degradative activity, and antigen processing capacity during GM-CSF driven differentiation of murine bone marrow 

Olatunde, Adesola C.; Abell, Laura P.; Landuyt, Ashley E.; Schwartz, Elizabeth Hiltbold (2022-03-11)
Dendritic cells (DC) are sentinels of the immune system, alerting and enlisting T cells to clear pathogenic threats. As such, numerous studies have demonstrated their effective uptake and proteolytic activities coupled ...