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College of Veterinary Medicine

Recent Submissions

Genomic responses to selection for tame/aggressive behaviors in the silver fox (Vulpes vulpes) 

Wang, Xu; Pipes, Lenore; Trut, Lyudmila N.; Herbeck, Yury; Vladimirova, Anastasiya V.; Gulevich, Rimma G.; Kharlamova, Anastasiya V.; Johnson, Jennifer L.; Acland, Gregory M.; Kukekova, Anna V.; Clark, Andrew G. (2020-07-24)
Animal domestication efforts have led to a shared spectrum of striking behavioral and morphological changes. To recapitulate this process, silver foxes have been selectively bred for tame and aggressive behaviors for more ...

Platelet gene therapy improves hemostatic function for integrin αIIbβ3-deficient dogs 

Fang, Juan; Jensen, Eric S.; Boudreauxe, Mary K.; Du, Lily M.; Hawkins, Troy B.; Koukouritaki, Sevasti B.; Cornetta, Kenneth; Wilcox, David A. (2020-05-20)
Activated blood platelets mediate the primary response to vascular injury. Although molecular abnormalities of platelet proteins occur infrequently, taken collectively, an inherited platelet defect accounts for a bleeding ...

Inadequate Reference Datasets Biased toward Short Non-epitopes Confound B-cell Epitope Prediction 

Rahman, Kh. Shamsur; Chowdhury, Erfan U.; Sachse, Konrad; Kaltenboeck, Bernhard; http://orcid.org/0000-0001-7243-8501 (2020-04-08)
X-ray crystallography has shown that an antibody paratope typically binds 15-22 amino acids (aa) of an epitope, of which 2-5 randomly distributed amino acids contribute most of the binding energy. In contrast, researchers ...

Altered microRNA Expression Profiles and Regulation of INK4A/CDKN2A Tumor Suppressor Genes in Canine Breast Cancer Models 

Mohammad, Farruk; Kabir, Lutful; Delnnocentes, Patricia; Bird, Richard Curtis (2020-01-16)
microRNA (miRNA) expression profiling of cancer versus normal cells may reveal the characteristic regulatory features that can be correlated to altered gene expression in both human and animal models of cancers. In this ...

Hydrogen sulfide cytoprotective signaling isendothelial nitric oxide synthase-nitricoxide dependent 

King, Adrienne L.; Polhemus, David J.; Bhushan, Shashi; Otsuka, Hiroyuki; Kondo, Kazuhisa; Nicholson, Chad K.; Bradley, Jessica M.; Islam, Kazi N.; Calvert, John W.; Tao, Ya-Xiong et al (2020-01-16)
Previous studies have demonstrated that hydrogen sulfide (H2S) protects against multiple cardiovascular disease states in a similar manner as nitric oxide (NO). H2S therapy also has been shown to augment NO bioavailability ...

Guide for Dissecting the Dog, A 

Rumph, Paul F. (2017-06-23)
A Guide for Dissecting the Dog has many distinctive features designed to aid students in their study of gross anatomy. In keeping with Dr. Fletcher’s original concept, descriptive material is minimal and most illustrations ...

Osteology of the White-Tailed Deer Odocoileus Virginianus, An 

Rumph, Paul Frederick (2016-07-09)
Because of the absence of a comprehensive description of the osseous anatomy of the white-tailed deer, this study was undertaken. The external morphology of each bone is described utilizing the current nomenclature presented ...