Browsing Harrison College of Pharmacy by Title
Now showing items 1-6 of 6
Active Site-labeled Prothrombin Inhibits Prothrombinase in Vitro and Thrombosis in Vivo
(2020-09-16)
Mouse and human prothrombin (ProT) active site specifically labeled with D-Phe-Pro-Arg-CH2Cl (FPR-ProT) inhibited
tissue factor-initiated thrombin generation in platelet-rich and
platelet-poor mouse and human plasmas. ...
Induction of C-X-C Chemokine Receptor Type 7 (CXCR7) Switches Stromal Cell-derived Factor-1 (SDF-1) Signaling and Phagocytic Activity in Macrophages Linked to Atherosclerosis*
(2020-01-02)
The discovery of CXCR7 as a new receptor for SDF-1 places
many previously described SDF-1 functions attributed to
CXCR4 in question, though whether CXCR7 acts as a signaling
or “decoy” receptor has been in debate. It ...
The P2Y(2) Nucleotide Receptor Mediates Tissue Factor Expression in Human Coronary Artery Endothelial Cells
(2020-09-16)
The discovery of the role of P2Y12 receptor in platelet aggregation leads to a new anti-thrombotic drug Plavix; however, little is known about non-platelet P2Y receptors in thrombosis.
This study tested the hypothesis ...
Purinergic P2Y2 Receptor Control of Tissue Factor Transcription in Human Coronary Artery Endothelial Cells NEW AP-1 TRANSCRIPTION FACTOR SITE AND NEGATIVE REGULATOR
(2020-04-08)
We recently reported that the P2Y2 receptor (P2Y2R) is the predominant nucleotide receptor expressed in human coronary artery endothelial cells (HCAEC) and that P2Y2R activation by ATP or UTP induces dramatic up-regulation ...
Should regression calibration or multiple imputation be used when calibrating different devices in a longitudinal study?
(2023-06-20)
In longitudinal studies, the devices used to measure exposures can change from visit to visit. Calibration studies, wherein a subset of participants is measured using both devices at follow-up, may be used to assess ...
The Size of college football stadiums and towns they are in: are all towns equipped for college football mass gathering?
(2024-04-09)
College football games had more than 47 million attendees in 2019. Mass gatherings in small communities can strain local resources, including emergency departments (EDs). The objective of this study was to conduct a ...