Browsing Harrison College of Pharmacy by Subject "Coagulation Factors Enzyme Kinetics Enzyme Mechanisms Fluorescence Protein-Protein Interactions Proteolytic Enzymes Prothrombin Serine Protease Thrombosis"

Now showing items 1-1 of 1

Active Site-labeled Prothrombin Inhibits Prothrombinase in Vitro and Thrombosis in Vivo

Kroh, Heather K.; Panizzi, Peter; Tchaikovski, Svetlana; Baird, T. Regan; Wei, Nancy; Krishnaswam, Sriram; Tans, Guido; Rosing, Jan; Furie, Bruce; Furie, Barbara C.; Bock, Paul E. (2020-09-16)

Mouse and human prothrombin (ProT) active site specifically labeled with D-Phe-Pro-Arg-CH2Cl (FPR-ProT) inhibited tissue factor-initiated thrombin generation in platelet-rich and platelet-poor mouse and human plasmas. ...