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Induction of C-X-C Chemokine Receptor Type 7 (CXCR7) Switches Stromal Cell-derived Factor-1 (SDF-1) Signaling and Phagocytic Activity in Macrophages Linked to Atherosclerosis*
(2020-01-02)
The discovery of CXCR7 as a new receptor for SDF-1 places
many previously described SDF-1 functions attributed to
CXCR4 in question, though whether CXCR7 acts as a signaling
or “decoy” receptor has been in debate. It ...
The P2Y(2) Nucleotide Receptor Mediates Tissue Factor Expression in Human Coronary Artery Endothelial Cells
(2020-09-16)
The discovery of the role of P2Y12 receptor in platelet aggregation leads to a new anti-thrombotic drug Plavix; however, little is known about non-platelet P2Y receptors in thrombosis.
This study tested the hypothesis ...