https://aurora.auburn.edu/handle/11200/44245 Sun, 05 Apr 2026 21:28:19 GMT 2026-04-05T21:28:19Z https://aurora.auburn.edu/handle/11200/49679 Hydrogen sulfide cytoprotective signaling isendothelial nitric oxide synthase-nitricoxide dependent Previous studies have demonstrated that hydrogen sulfide (H2S) protects against multiple cardiovascular disease states in a similar manner as nitric oxide (NO). H2S therapy also has been shown to augment NO bioavailability and signaling. The purpose of this study was to investigate the impact of H2S deficiency on endothelial NO synthase (eNOS) function, NO production, and ischemia/reperfusion (I/R) injury. We found that mice lacking the H2S-producing enzyme cystathionine γ-lyase (CSE) exhibit elevated oxidative stress, dysfunctional eNOS, diminished NO levels, and exacerbated myocardial and hepatic I/R injury. In CSE KO mice, acute H2S therapy restored eNOS function and NO bioavailability and attenuated I/R injury. In addition, we found that H2S therapy fails to protect against I/R in eNOS phosphomutant mice (S1179A). Our results suggest that H2S-mediated cytoprotective signaling in the setting of I/R injury is dependent in large part on eNOS activation and NO generation. https://aurora.auburn.edu/handle/11200/49679 https://aurora.auburn.edu/handle/11200/48844 Guide for Dissecting the Dog, A A Guide for Dissecting the Dog has many distinctive features designed to aid students in their study of gross anatomy. In keeping with Dr. Fletcher’s original concept, descriptive material is minimal and most illustrations and photographs are designed to facilitate the dissection. Dependence on the excellent figures and descriptions in anatomy texts such as Miller’s Anatomy of the Dog by Dr. Howard Evans or Textbook of Veterinary Anatomy by Dyce, Sack and Wensing is by design. We have included several conceptual sketches that present ideas not available elsewhere in veterinary literature. When anatomical terms are introduced, they are underlined. Dissection instructions are presented in bold blue print and brief clinical comments are presented in italicized red print. Students dissect the male and female alternately so they can view and study structures on each sex before the specimens are altered or destroyed by subsequent dissection. The nomenclature throughout is that of Nomina Anatomica Veterinaria. The entire dissection sequence presented in A Guide for Dissecting the Dog can be completed in 96 hours. This book is a work in progress and will be updated periodically. With text by Thomas F. Fletcher, Paul F. Rumph, Phillip D. Garrett and Gerald R. Bratton; drawings by Phillip D. Garrett; and photos by Elizabeth A. Lantz, Elaine S. Coleman, D. Ray Wilhite and Paul F. Rumph. Compiled by Paul F. Rumph, DVM, MS. https://aurora.auburn.edu/handle/11200/48844 https://aurora.auburn.edu/handle/11200/48623 Osteology of the White-Tailed Deer Odocoileus Virginianus, An Because of the absence of a comprehensive description of the osseous anatomy of the white-tailed deer, this study was undertaken. The external morphology of each bone is described utilizing the current nomenclature presented in Nomina Anatomica Veterinaria. Bones obtained from five male and five female deer were studied. The skull is described as a whole and its features are characterized as seen from several views. Bones of the vertebral column are considered in regions with bones and features not characteristic of the series presented individually. The components of the appendicular skeleton are presented individually. This thesis confirms the presence of a unique facial vacuity on the facial portion of the skull, a first carpal bone and vestigial second and fifth metacarpal bones. The results report the presence of a single os cordis and distal sesamoid bones the presence of which had not been previously recorded. The condition of the fibula was examined and its variable status is reported. Both the written description and the drawings should be useful to law enforcement officials and archeologists in identifying bones as those of the white-tailed deer. Accompanied by pen and ink drawings. Master's Thesis from Auburn University. Sat, 09 Jul 2016 00:00:00 GMT https://aurora.auburn.edu/handle/11200/48623 2016-07-09T00:00:00Z