Browsing Harrison College of Pharmacy by Author "Ma, Wanshu"

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Induction of C-X-C Chemokine Receptor Type 7 (CXCR7) Switches Stromal Cell-derived Factor-1 (SDF-1) Signaling and Phagocytic Activity in Macrophages Linked to Atherosclerosis*

Ma, Wanshu; Liu, Yiwei; Ellison, Nicholas; Shen, Jianzhong (2020-01-02)

The discovery of CXCR7 as a new receptor for SDF-1 places many previously described SDF-1 functions attributed to CXCR4 in question, though whether CXCR7 acts as a signaling or “decoy” receptor has been in debate. It ...

The P2Y(2) Nucleotide Receptor Mediates Tissue Factor Expression in Human Coronary Artery Endothelial Cells

Ding, Ling; Ma, Wanshu; Littmann, Timothy; Camp, Riley; Shen, Jianzhong (2020-09-16)

The discovery of the role of P2Y12 receptor in platelet aggregation leads to a new anti-thrombotic drug Plavix; however, little is known about non-platelet P2Y receptors in thrombosis. This study tested the hypothesis ...